Paulina Likus

Master Paulina Likus – PhD student in biological sciences. A graduate of first and second degree biology at the Pedagogical University of Commission of National Education in Krakow.

My main interest is microbiology, especially the impact of antibiotics, chemotherapeutics and natural substances on the development of microorganisms. Further scientific interests include ecotoxicology, human biomonitoring and public health. Currently, I exercise my laboratory competences as an employee of the Laboratory Diagnostics Department of the District Hospital in Chrzanów.

In the research project, I want to investigate the impact of newly synthesized compounds resulting from the condensation of a series of rhodanine-3-carboxyalkyl acids with substituted 2-chloroquinoline-3-carboxaldehydes on multidrug-resistant Gram-negative bacteria from the Enterobacteriaceae family producing extended-spectrum β-lactamases (ESBL) and Gram – positive bacteria from the Staphylococcaceae family.

The research will include the following stages: isolation of bacilli from clinical material with extended antibiotic resistance, determination of the growth kinetics of these bacteria in the presence of newly synthesized compounds, analysis of changes in the gene transcriptome.